Upregulation of Cardiac IL-10 and Downregulation of IFN-γ in Balb/c IL-4−/− in Acute Chagasic Myocarditis due to Colombian Strain of Trypanosoma cruzi

• Main Authors: Marcos Vinicius da Silva (Author), Vera Lúcia de Almeida (Author), Wendyson Duarte de Oliveira (Author), Natália Carasek Matos Cascudo (Author), Pollyana Guimarães de Oliveira (Author), Crislaine Aparecida da Silva (Author), Aline Cristina Souza da Silva (Author), Maria Luíza Gonçalves dos Reis Monteiro (Author), Rosana Rosa Miranda Correa (Author), Milton Adriano Pelli Oliveira (Author), Ruy de Sousa Lino-Júnior (Author), Mara Rúbia Nunes Celes (Author), Juliana Reis Machado (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inflammatory response in Chagas disease is related to parasite and host factors. However, immune system regulation has not been fully elucidated. Thus, this study is aimed at evaluating IL-4 influence on acute phase of Trypanosoma cruzi experimental infection through dosage of cytokine levels in car...