Generated SecPen_NY-ESO-1_ubiquitin-pulsed dendritic cell cancer vaccine elicits stronger and specific T cell immune responses

• Main Authors: Yunkai Yang (Author), Xiaohan Guo (Author), Bo Hu (Author), Peng He (Author), Xiaowu Jiang (Author), Zuohuan Wang (Author), Huaxing Zhu (Author), Lina Hu (Author), Minghua Yu (Author), Meiqing Feng (Author)
• Format: Book
• Published: Elsevier, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dendritic cell-based cancer vaccines (DC vaccines) have been proved efficient and safe in immunotherapy of various cancers, including melanoma, ovarian and prostate cancer. However, the clinical responses were not always satisfied. Here we proposed a novel strategy to prepare DC vaccines. In the pre...