Chiral Hydroxy Metabolite of Mebendazole: Analytical and Semi-Preparative High-Performance Liquid Chromatography Resolution and Chiroptical Properties

• Main Authors: Paolo Guglielmi (Author), Gaia Pulitelli (Author), Francesca Arrighi (Author), Daniela Secci (Author), Marco Pierini (Author), Roberto Cirilli (Author)
• Format: Book
• Published: MDPI AG, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mebendazole (<b>MBZ</b>) is a benzimidazole carbamate anthelmintic used worldwide for the treatment and prevention of parasitic disorders in animals and humans. A large number of in vivo and in vitro studies have demonstrated that <b>MBZ</b> also has anticancer activity in mu...