Pharmacophore mapping studies on indolizine derivatives as 15-LOX inhibitors
This investigation analyzes the common chemical features for 15-lipoxygenase (15-LOX) inhibitors to develop ligand-based pharmacophore models for lipoxygenase inhibitory activity. The present model is based on a dataset of 47 indolizine derivatives that exhibit inhibition against 15-LOX enzyme isola...
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Faculty of Pharmacy, Cairo University,
2015-06-01T00:00:00Z.
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