Development and pharmacokinetic assessment of a fully canine anti-PD-1 monoclonal antibody for comparative translational research in dogs with spontaneous tumors

• Κύριοι συγγραφείς: Sho Yoshimoto (Συγγραφέας), Nicholas Chester (Συγγραφέας), Ailian Xiong (Συγγραφέας), Enrico Radaelli (Συγγραφέας), Hong Wang (Συγγραφέας), Marc Brillantes (Συγγραφέας), Gayathri Gulendran (Συγγραφέας), Patrick Glassman (Συγγραφέας), Don L. Siegel (Συγγραφέας), Nicola J. Mason (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

ABSTRACTPD-1 checkpoint inhibitors have revolutionized the treatment of patients with different cancer histologies including melanoma, renal cell carcinoma, and non-small cell lung carcinoma. However, only a subset of patients show a dramatic clinical response to treatment. Despite intense biomarker...