Dimethyl Fumarate Induces Metabolic Crisie to Suppress Pancreatic Carcinoma

• Main Authors: Kaiyuan Chen (Author), Shanshan Wu (Author), Sisi Ye (Author), Huimin Huang (Author), Yi Zhou (Author), Hongfei Zhou (Author), Shijia Wu (Author), Yefan Mao (Author), Fugen Shangguan (Author), Linhua Lan (Author), Bicheng Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dimethyl fumarate (DMF) is an approved drug used in the treatment of multiple sclerosis (MS) and psoriasis therapy. Multiple studies have demonstrated other pharmacological activities of DMF such as an anti-cancer agent. In particular, studies have shown that DMF can modulate the NRF2/HO1/NQO1 antio...