Role of Caveolin 1, E-Cadherin, Enolase 2 and PKCalpha on resistance to methotrexate in human HT29 colon cancer cells

• Main Authors: Noé Véronique (Author), Morales Cristina (Author), Selga Elisabet (Author), Peinado Miguel A (Author), Ciudad Carlos J (Author)
• Format: Book
• Published: BMC, 2008-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Methotrexate is one of the earliest cytotoxic drugs used in cancer therapy, and despite the isolation of multiple other folate antagonists, methotrexate maintains its significant role as a treatment for different types of cancer and...