Role of Caveolin 1, E-Cadherin, Enolase 2 and PKCalpha on resistance to methotrexate in human HT29 colon cancer cells

• Autores principales: Noé Véronique (Autor), Morales Cristina (Autor), Selga Elisabet (Autor), Peinado Miguel A (Autor), Ciudad Carlos J (Autor)
• Formato: Libro
• Publicado: BMC, 2008-08-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Methotrexate is one of the earliest cytotoxic drugs used in cancer therapy, and despite the isolation of multiple other folate antagonists, methotrexate maintains its significant role as a treatment for different types of cancer and...