Convection-Enhanced Delivery of a First-in-Class Anti-β1 Integrin Antibody for the Treatment of High-Grade Glioma Utilizing Real-Time Imaging

Introduction: OS2966 is a first-in-class, humanized and de-immunized monoclonal antibody which targets the adhesion receptor subunit, CD29/β1 integrin. CD29 expression is highly upregulated in glioblastoma and has been shown to drive tumor progression, invasion, and resistance to multiple modalities...

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Bibliographic Details
Main Authors: Chibueze D. Nwagwu (Author), Amanda V. Immidisetti (Author), Gabriela Bukanowska (Author), Michael A. Vogelbaum (Author), Anne-Marie Carbonell (Author)
Format: Book
Published: MDPI AG, 2020-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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