Rare variants in the splicing regulatory elements of EXOC3L4 are associated with brain glucose metabolism in Alzheimer's disease

• Main Authors: Jason E. Miller (Author), Manu K. Shivakumar (Author), Younghee Lee (Author), Seonggyun Han (Author), Emrin Horgousluoglu (Author), Shannon L. Risacher (Author), Andrew J. Saykin (Author), Kwangsik Nho (Author), Dokyoon Kim (Author), for the Alzheimer's Disease Neuroimaging Initiative (Author)
• פורמט: ספר
• יצא לאור: BMC, 2018-09-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Abstract Background Alzheimer's disease (AD) is one of the most common neurodegenerative diseases that causes problems related to brain function. To some extent it is understood on a molecular level how AD arises, however there are a lack of biomarkers that can be used for early diagnosis. Two...