Does Evolocumab, as a PCSK9 Inhibitor, Ameliorate the Lipid Profile in Familial Hypercholesterolemia Patients? A Meta-Analysis of Randomized Controlled Trials

Proprotein convertase subtilisin-kexin type 9 (PCSK9) is a member of regulatory serine proteases which is mostly expressed in liver. In the physiological condition, LDL-C binds to LDL receptors (LDLRs) and via endocytosis, LDLRs are degraded. PCSK9 binds to the epidermal growth factor-like repeat A...

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Main Authors: Seyyed Majid Eslami (Author), Shekoufeh Nikfar (Author), Maryam Ghasemi (Author), Mohammad Abdollahi (Author)
Format: Book
Published: Frontiers Media S.A., 2017-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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