Longitudinal CITE-Seq profiling of chronic lymphocytic leukemia during ibrutinib treatment: evolution of leukemic and immune cells at relapse

Longitudinal CITE-Seq profiling of chronic lymphocytic leukemia during ibrutinib treatment: evolution of leukemic and immune cells at relapse

Abstract Background Ibrutinib, an irreversible Bruton Tyrosine Kinase (BTK) inhibitor, has revolutionized Chronic Lymphocytic Leukemia (CLL) treatment, but resistances to ibrutinib have emerged, whether related or not to BTK mutations. Patterns of CLL evolution under ibrutinib therapy are well chara...

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Main Authors: Sarah Cadot (Author), Carine Valle (Author), Marie Tosolini (Author), Frederic Pont (Author), Laetitia Largeaud (Author), Camille Laurent (Author), Jean Jacques Fournie (Author), Loic Ysebaert (Author), Anne Quillet-Mary (Author)
Format: Book
Published: BMC, 2020-12-01T00:00:00Z.
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3rd Floor Main Library

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