Seed- and Soil-Dependent Differences in Murine Breast Tumor Microenvironments Dictate Anti-PD-L1 IgG Delivery and Therapeutic Efficacy

Seed- and Soil-Dependent Differences in Murine Breast Tumor Microenvironments Dictate Anti-PD-L1 IgG Delivery and Therapeutic Efficacy

We sought to determine if Stephen Paget's "seed and soil" hypothesis of organ-preference patterns of cancer metastasis can explain the development of heterogeneity in a tumor microenvironment (TME) as well as immunotherapeutic delivery and efficacy. We established single-cell-derived...

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Main Authors: Yan Ting Liu (Author), Shreya Goel (Author), Megumi Kai (Author), Jose Alberto Moran Guerrero (Author), Thao Nguyen (Author), Junhua Mai (Author), Haifa Shen (Author), Arturas Ziemys (Author), Kenji Yokoi (Author)
Format: Book
Published: MDPI AG, 2021-04-01T00:00:00Z.
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3rd Floor Main Library

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