Clinical and genetic findings in two siblings with X-Linked agammaglobulinemia and bronchiolitis obliterans: a case report

• Main Authors: Ronaldo da Silva Francisco Junior (Author), Guilherme Loss de Morais (Author), Joseane Biso de Carvalho (Author), Cristina dos Santos Ferreira (Author), Alexandra Lehmkuhl Gerber (Author), Ana Paula de C Guimarães (Author), Flávia Anisio Amendola (Author), Fernanda Pinto-Mariz (Author), Zilton Farias Meira de Vasconcelos (Author), Ekaterini Simões Goudouris (Author), Ana Tereza Ribeiro de Vasconcelos (Author)
• 格式: 图书
• 出版: BMC, 2022-04-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Abstract Background X-linked agammaglobulinemia (XLA) is an Inborn Errors of Immunity (IEI) characterized by pan-hypogammaglobulinemia and low numbers of B lymphocytes due to mutations in BTK gene. Usually, XLA patients are not susceptible to respiratory tract infections by viruses and do not presen...