Efflux Activity Differentially Modulates the Levels of Isoniazid and Rifampicin Resistance among Multidrug Resistant and Monoresistant Mycobacterium tuberculosis Strains

• Main Authors: Diana Machado (Author), João Perdigão (Author), Isabel Portugal (Author), Marco Pieroni (Author), Pedro A. Silva (Author), Isabel Couto (Author), Miguel Viveiros (Author)
• Format: Book
• Published: MDPI AG, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

With the growing body of knowledge on the contribution of efflux activity to Mycobacterium tuberculosis drug resistance, increased attention has been given to the use of efflux inhibitors as adjuvants of tuberculosis therapy. Here, we investigated how efflux activity modulates the levels of efflux b...