Influence of lipopolysaccharides on autophagy and inflammation in pancreatic islet cells of mice fed by high-fat diet

• Main Authors: Hongwei Jiang (Author), Yujin Ma (Author), Liujun Fu (Author), Jie Wang (Author), Linlei Wang (Author), Menglin Fan (Author), Ke Huang (Author), Yingyu Zhang (Author), Huifang Peng (Author)
• Format: Book
• Published: SAGE Publishing, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of this study was to confirm whether chronic low-grade inflammation could induce autophagy and damage in islet cells. The high-fat diet (HF) and low-dose lipopolysaccharides (LPS) were used to simulate chronic inflammation. Islet function was observed, the expression of autophagy-related pro...