Translating preventive chemotherapy prevalence thresholds for Schistosoma mansoni from the Kato-Katz technique into the point-of-care circulating cathodic antigen diagnostic test.

• Main Authors: Oliver Bärenbold (Author), Amadou Garba (Author), Daniel G Colley (Author), Fiona M Fleming (Author), Ayat A Haggag (Author), Reda M R Ramzy (Author), Rufin K Assaré (Author), Edridah M Tukahebwa (Author), Jean B Mbonigaba (Author), Victor Bucumi (Author), Biruck Kebede (Author), Makoy S Yibi (Author), Aboulaye Meité (Author), Jean T Coulibaly (Author), Eliézer K N'Goran (Author), Louis-Albert Tchuem Tchuenté (Author), Pauline Mwinzi (Author), Jürg Utzinger (Author), Penelope Vounatsou (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Intervention guidelines against Schistosoma mansoni are based on the Kato-Katz technique. However, Kato-Katz thick smears show low sensitivity, especially for light-intensity infections. The point-of-care circulating cathodic antigen (POC-CCA) is a promising rapid diag...