Statistical evaluation of absolute change versus responder analysis in clinical trials

• Main Authors: Peijin Wang (Author), Sarah Peskoe (Author), Rebecca Byrd (Author), Patrick Smith (Author), Rachel Breslin (Author), Shein-Chung Chow (Author)
• Format: Book
• Published: Compuscript Ltd, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In clinical trials, the primary analysis is often either a test of absolute/relative change in a measured outcome or a corresponding responder analysis. Although each of these tests may be reasonable, determining which test is most suitable for a particular research study remains an open question. T...