A pharmacokinetics‐based approach to the monitoring of patient adherence to atorvastatin therapy

• Autors principals: Gellért Balázs Karvaly (Autor), István Karádi (Autor), István Vincze (Autor), Michael N. Neely (Autor), Eszter Trojnár (Autor), Zoltán Prohászka (Autor), Éva Imreh (Autor), Barna Vásárhelyi (Autor), András Zsáry (Autor)
• Format: Llibre
• Publicat: Wiley, 2021-10-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Abstract The inadequate adherence of patients whose hyperlipidemia is treated with atorvastatin (ATR) to medical instructions presents a serious health risk. Our aim was to develop a flexible approach based on therapeutic drug monitoring (TDM), nonparametric population pharmacokinetic modeling, and...