Efficacy of Trimethoprim-Sulfamethoxazole in Combination with an Echinocandin as a First-Line Treatment Option for Pneumocystis Pneumonia: A Systematic Review and Meta-Analysis

• Main Authors: Hideo Kato (Author), Mao Hagihara (Author), Nobuhiro Asai (Author), Takumi Umemura (Author), Yuichi Shibata (Author), Jun Hirai (Author), Yuka Yamagishi (Author), Takuya Iwamoto (Author), Hiroshige Mikamo (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although combination therapy using trimethoprim-sulfamethoxazole (TMP-SMX) plus echinocandins has been reported to reduce the mortality of patients with pneumocystis pneumonia (PCP), it remains unclear whether it is more effective than TMP-SMX monotherapy, the current first-line treatment for this d...