Proteomics unite traditional toxicological assessment methods to evaluate the toxicity of iron oxide nanoparticles

• Main Authors: Junyuan Han (Author), Yongzhang Tian (Author), Minghan Wang (Author), Yajuan Li (Author), Jiye Yin (Author), Wensheng Qu (Author), Changhui Yan (Author), Rigao Ding (Author), Yongbiao Guan (Author), Quanjun Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Iron oxide nanoparticles (IONPs) are the first generation of nanomaterials approved by the Food and Drug Administration for use as imaging agents and for the treatment of iron deficiency in chronic kidney disease. However, several IONPs-based imaging agents have been withdrawn because of toxic effec...