Pharmacokinetics, Pharmacodynamics and Antiviral Efficacy of the MEK Inhibitor Zapnometinib in Animal Models and in Humans
The mitogen-activated protein kinase (MEK) inhibitor zapnometinib is in development to treat acute viral infections like COVID-19 and influenza. While the antiviral efficacy of zapnometinib is well documented, further data on target engagement/pharmacodynamics (PD) and pharmacokinetics (PK) are need...
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Main Authors: | Julia Koch-Heier (Author), Annika Schönsiegel (Author), Lara Maria Waidele (Author), Julian Volk (Author), Yvonne Füll (Author), Christian Wallasch (Author), Sebastian Canisius (Author), Michael Burnet (Author), Oliver Planz (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2022-06-01T00:00:00Z.
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