Immunoregulatory effects of indole-3-carbinol on monocyte-derived macrophages in systemic lupus erythematosus: A crucial role for aryl hydrocarbon receptor

• 主要な著者: Saeed Mohammadi (著者), Ali Memarian (著者), Sima Sedighi (著者), Nasser Behnampour (著者), Yaghoub Yazdani (著者)
• フォーマット: 図書
• 出版事項: Taylor & Francis Group, 2018-07-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Macrophages are versatile phagocytic cells in immune system with immunoregulatory functions. However, the removal of apoptotic cells by macrophages is disturbed in systemic lupus erythematosus (SLE). Aryl hydrocarbon receptor (AhR) is a ligand-activated cytoplasmic receptor and transcription factor...