A Novel Spider Toxin Inhibits Fast Inactivation of the Nav1.9 Channel by Binding to Domain III and Domain IV Voltage Sensors

• Asıl Yazarlar: Shuijiao Peng (Yazar), Minzhi Chen (Yazar), Zhen Xiao (Yazar), Xin Xiao (Yazar), Sen Luo (Yazar), Songping Liang (Yazar), Xi Zhou (Yazar), Zhonghua Liu (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2021-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Venomous animals have evolved to produce peptide toxins that modulate the activity of voltage-gated sodium (Nav) channels. These specific modulators are powerful probes for investigating the structural and functional features of Nav channels. Here, we report the isolation and characterization of δ-t...