Design, Synthesis and Biochemical Evaluation of Novel Ethanoanthracenes and Related Compounds to Target Burkitt's Lymphoma

• Main Authors: Andrew J. Byrne (Author), Sandra A. Bright (Author), James P. McKeown (Author), John E. O'Brien (Author), Brendan Twamley (Author), Darren Fayne (Author), D. Clive Williams (Author), Mary J. Meegan (Author)
• Format: Book
• Published: MDPI AG, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lymphomas (cancers of the lymphatic system) account for 12% of malignant diseases worldwide. Burkitt’s lymphoma (BL) is a rare form of non-Hodgkin’s lymphoma in which the cancer starts in the immune B-cells. We report the synthesis and preliminary studies on the antiproliferative...