Benzimidazoles Containing Piperazine Skeleton at C-2 Position as Promising Tubulin Modulators with Anthelmintic and Antineoplastic Activity

Benzimidazoles Containing Piperazine Skeleton at C-2 Position as Promising Tubulin Modulators with Anthelmintic and Antineoplastic Activity

Benzimidazole anthelmintic drugs hold promise for repurposing as cancer treatments due to their interference with tubulin polymerization and depolymerization, manifesting anticancer properties. We explored the potential of benzimidazole compounds with a piperazine fragment at C-2 as tubulin-targetin...

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Main Authors: Kameliya Anichina (Author), Anelia Mavrova (Author), Dimitar Vuchev (Author), Galya Popova-Daskalova (Author), Giada Bassi (Author), Arianna Rossi (Author), Monica Montesi (Author), Silvia Panseri (Author), Filip Fratev (Author), Emilia Naydenova (Author)
Format: Book
Published: MDPI AG, 2023-10-01T00:00:00Z.
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3rd Floor Main Library

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