Reintroduction of DJ-1 in Müller Cells Inhibits Retinal Degeneration in the DJ-1 Deficient Retina

• Main Authors: Naouel Gharbi (Author), Dagne Røise (Author), Jorunn-Elise Førre (Author), Amanda J. Edson (Author), Helena A. Hushagen (Author), Valentina Tronci (Author), Ann-Kristin Frøyset (Author), Kari E. Fladmark (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The eye is continuously under oxidative stress due to high metabolic activity and reactive oxygen species generated by daily light exposure. The redox-sensitive protein DJ-1 has proven to be essential in order to protect retina and retinal pigment epithelium (RPE) from oxidative-stress-induced degen...