Synthesis of Novel 1,4- Dihydropyridine Derivatives Bearing Biphenyl-2'-Tetrazole Substitution as Potential Dual Angiotensin II Receptors and Calcium Channel Blockers

• Main Authors: Javid Shahbazi Mojarrad (Author), Zahra Zamani (Author), Hossein Nazemiyeh (Author), Saeed Ghasemi (Author), Davoud Asgari (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2011-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: We report the synthesis of novel 1,4-dihydropyridine derivatives containing biphenyl-2'-tetrazole moieties. We hypothesized that merging the key structural elements present in an AT1 receptor antagonist with key structural elements in 1,4-dihydropyridine calcium channel blockers w...