Effective control of early Zika virus replication by Dengue immunity is associated to the length of time between the 2 infections but not mediated by antibodies.

• Main Authors: Crisanta Serrano-Collazo (Author), Erick X Pérez-Guzmán (Author), Petraleigh Pantoja (Author), Mariah A Hassert (Author), Idia V Rodríguez (Author), Luis Giavedoni (Author), Vida Hodara (Author), Laura Parodi (Author), Lorna Cruz (Author), Teresa Arana (Author), Melween I Martínez (Author), Laura White (Author), James D Brien (Author), Aravinda de Silva (Author), Amelia K Pinto (Author), Carlos A Sariol (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Little is known about the contribution of virus-specific and cross-reacting antibodies (Abs) or the cellular immune response generated by a primary dengue (DENV) infection on the course of a secondary zika (ZIKV) infection in vivo. Here we show that the length of time between DENV/ZIKV infections ha...