Elucidation of Inverse Agonist Activity of Bilastine

• Principais autores: Hiroyuki Mizuguchi (Autor), Tomoharu Wakugawa (Autor), Hisato Sadakata (Autor), Seiichiro Kamimura (Autor), Mai Takemoto (Autor), Tomomi Nakagawa (Autor), Masami Yabumoto (Autor), Yoshiaki Kitamura (Autor), Noriaki Takeda (Autor), Hiroyuki Fukui (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2020-06-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

H₁-antihistamines antagonize histamine and prevent it from binding to the histamine H₁ receptor (H1R). Some of them also act as inverse agonists, which are more potent than pure antagonists because they suppress the constitutive H1R activity. Bilastine i...