Acidification of rat TRPV1 alters the kinetics of capsaicin responses

• Main Authors: Faltynek Connie R (Author), Han Ping (Author), Jarvis Michael F (Author), Neelands Torben R (Author), Surowy Carol S (Author)
• Format: Book
• Published: SAGE Publishing, 2005-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>TRPV1 (vanilloid receptor 1) receptors are activated by a variety of ligands such as capsaicin, as well as by acidic conditions and temperatures above 42°C. These activators can enhance the potency of one another, shifting the activation curve for TRPV1 to the le...