Association of matrix metalloprotease 1, 3, and 12 polymorphisms with rheumatic heart disease in a Chinese Han population

• Main Authors: Wei Hu (Author), Yujia Ye (Author), Yirui Yin (Author), Peng Sang (Author), Linhua Li (Author), Jing Wang (Author), Wen Wan (Author), Rui Li (Author), Xiangfeng Bai (Author), Yuehui Xie (Author), Zhaohui Meng (Author)
• Format: Book
• Published: BMC, 2018-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Rheumatic heart disease (RHD) is an autoimmune disease triggered by acute rheumatic fever (ARF). Matrix metalloproteinases (MMPs) play an important role in the modulation of immune responses. The purpose of this study was to evaluate the association of MMP1, 3, and 12 promoter po...