Tamoxifen is effective in the treatment of Leishmania amazonensis infections in mice.

• Egile Nagusiak: Danilo C Miguel (Egilea), Jenicer K U Yokoyama-Yasunaka (Egilea), Silvia R B Uliana (Egilea)
• Formatua: Liburua
• Argitaratua: Public Library of Science (PLoS), 2008-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

BACKGROUND: Chemotherapy is still a critical issue in the management of leishmaniasis. Until recently, pentavalent antimonials, amphotericin B or pentamidine compounded the classical arsenal of treatment. All these drugs are toxic and have to be administered by the parenteral route. Tamoxifen has be...