The Use of a Non-Conventional Long-Lived Gallium Radioisotope ⁶⁶Ga Improves Imaging Contrast of EGFR Expression in Malignant Tumours Using DFO-ZEGFR:2377 Affibody Molecule

• Main Authors: Maryam Oroujeni (Author), Tianqi Xu (Author), Katherine Gagnon (Author), Sara S. Rinne (Author), Jan Weis (Author), Javad Garousi (Author), Ken G. Andersson (Author), John Löfblom (Author), Anna Orlova (Author), Vladimir Tolmachev (Author)
• Format: Book
• Published: MDPI AG, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Epidermal growth factor receptor (EGFR) is overexpressed in many malignancies. EGFR-targeted therapy extends survival of patients with disseminated cancers. Radionuclide molecular imaging of EGFR expression would make EGFR-directed treatment more personalized and therefore more efficient. A previous...