<i>TYMS</i> 3'-UTR Polymorphism: A Novel Association with FOLFIRINOX-Induced Neurotoxicity in Pancreatic Cancer Patients

• Main Authors: Marina Emelyanova (Author), Ilya Pokataev (Author), Igor Shashkov (Author), Elena Kopantseva (Author), Vladimir Lyadov (Author), Rustam Heydarov (Author), Vladimir Mikhailovich (Author)
• Format: Book
• Published: MDPI AG, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pancreatic ductal adenocarcinoma (PDAC) is a highly fatal malignancy that has the worst 5-year survival rate of all of the common malignant tumors. Surgery, chemotherapy, and/or chemoradiation remain the main tactics for PDAC treatment. The efficacy of chemotherapy is often compromised because of th...