Integrative transcriptomic and network pharmacology analysis reveals the neuroprotective role of BYHWD through enhancing autophagy by inhibiting Ctsb in intracerebral hemorrhage mice

• Main Authors: Yiqing Cai (Author), Zhe Yu (Author), Xueping Yang (Author), Weikang Luo (Author), En Hu (Author), Teng Li (Author), Wenxin Zhu (Author), Yang Wang (Author), Tao Tang (Author), Jiekun Luo (Author)
• Format: Book
• Published: BMC, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background In this study, we aimed to combine transcriptomic and network pharmacology to explore the crucial mRNAs and specific regulatory molecules of Buyang Huanwu Decoction (BYHWD) in intracerebral hemorrhage (ICH) treatment. Methods C57BL/6 mice were randomly divided into three groups:...