Comparison of the Mismatch Repair System between Primary and Metastatic Colorectal Cancers Using Immunohistochemistry

• Main Authors: Jiyoon Jung (Author), Youngjin Kang (Author), Yoo Jin Lee (Author), Eojin Kim (Author), Bokyung Ahn (Author), Eunjung Lee (Author), Joo Young Kim (Author), Jeong Hyeon Lee (Author), Youngseok Lee (Author), Chul Hwan Kim (Author), Yang-Seok Chae (Author)
• Format: Book
• Published: Korean Society of Pathologists & the Korean Society for Cytopathology, 2017-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background Colorectal cancer (CRC) is one of the most common malignancies worldwide. Approximately 10%-15% of the CRC cases have defective DNA mismatch repair (MMR) genes. Although the high level of microsatellite instability status is a predictor of favorable outcome in primary CRC, little is known...