Jian-Ti-Kang-Yi decoction alleviates poly(I:C)-induced pneumonia by inhibiting inflammatory response, reducing oxidative stress, and modulating host metabolism

• Main Authors: Huantian Cui (Author), Yuming Wang (Author), Bolun Yu (Author), Yulin Wu (Author), Gaijun Zhang (Author), Junli Guo (Author), Junyu Luo (Author), Qin Li (Author), Xiaojuan Li (Author), Wenju He (Author), Weibo Wen (Author), Jiabao Liao (Author), Dongqiang Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Jian-Ti-Kang-Yi decoction (JTKY) is widely used in the treatment of COVID-19. However, the protective mechanisms of JTKY against pneumonia remain unknown. In this study, polyinosinic-polycytidylic acid (poly(I:C)), a mimic of viral dsRNA, was used to induce pneumonia in mice; the therapeutic effects...