Design and use of an ex vivo peripheral simulating bioreactor system for pharmacokinetic analysis of a drug coated stent

• Main Authors: Danyi Chen (Author), Colin Krinsky (Author), Mollie Phillips (Author), Catherine Allred (Author), Ava Khan (Author), Linda B. Liu (Author), Uwe Christians (Author), Saami K. Yazdani (Author)
• Format: Book
• Published: Wiley, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Currently, there are no ex vivo systems that can model the motion of peripheral arteries and allow for the evaluation of pharmacokinetics (PK) of endovascular devices. The objective of this study was to develop a novel peripheral simulating bioreactor system to evaluate drug pharmacokinetic...