Rapid, Single-Cell Analysis and Discovery of Vectored mRNA Transfection In Vivo with a loxP-Flanked tdTomato Reporter Mouse

Rapid, Single-Cell Analysis and Discovery of Vectored mRNA Transfection In Vivo with a loxP-Flanked tdTomato Reporter Mouse

mRNA therapeutics hold promise for the treatment of diseases requiring intracellular protein expression and for use in genome editing systems, but mRNA must transfect the desired tissue and cell type to be efficacious. Nanoparticle vectors that deliver the mRNA are often evaluated using mRNA encodin...

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Main Authors: Kevin J. Kauffman (Author), Matthias A. Oberli (Author), J. Robert Dorkin (Author), Juan E. Hurtado (Author), James C. Kaczmarek (Author), Shivani Bhadani (Author), Jeff Wyckoff (Author), Robert Langer (Author), Ana Jaklenec (Author), Daniel G. Anderson (Author)
Format: Book
Published: Elsevier, 2018-03-01T00:00:00Z.
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3rd Floor Main Library

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