Bile Acids Induce Alterations in Mitochondrial Function in Skeletal Muscle Fibers

• Main Authors: Johanna Abrigo (Author), Hugo Olguín (Author), Danae Gutierrez (Author), Franco Tacchi (Author), Marco Arrese (Author), Daniel Cabrera (Author), Mayalen Valero-Breton (Author), Alvaro A. Elorza (Author), Felipe Simon (Author), Claudio Cabello-Verrugio (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cholestatic chronic liver disease is characterized by developing sarcopenia and elevated serum levels of bile acids. Sarcopenia is a skeletal muscle disorder with the hallmarks of muscle weakness, muscle mass loss, and muscle strength decline. Our previous report demonstrated that deoxycholic acid (...