13-(2-Methylbenzyl) Berberine Is a More Potent Inhibitor of MexXY-Dependent Aminoglycoside Resistance than Berberine
We previously showed that berberine attenuates MexXY efflux-dependent aminoglycoside resistance in <i>Pseudomonas aeruginosa</i>. Here, we aimed to synthesize berberine derivatives with higher MexXY inhibitory activities. We synthesized 11 berberine derivatives, of which 13-(2-methylbenz...
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Main Authors: | Kenta Kotani (Author), Mio Matsumura (Author), Yuji Morita (Author), Junko Tomida (Author), Ryo Kutsuna (Author), Kunihiko Nishino (Author), Shuji Yasuike (Author), Yoshiaki Kawamura (Author) |
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Format: | Book |
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MDPI AG,
2019-11-01T00:00:00Z.
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