Forsythiaside B ameliorates coagulopathies in a rat model of sepsis through inhibition of the formation of PAD4-dependent neutrophil extracellular traps

• Autori principali: Wenju He (Autore), Qiang Xi (Autore), Huantian Cui (Autore), Pingping Zhang (Autore), Rui Huang (Autore), Taihuan Wang (Autore), Dongqiang Wang (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Forsythiaside B (FTB) is one of the main components of Forsythia suspensa (Thunb.) Vahl and exerts anti-inflammatory and anti-oxidative effects. However, its mechanism of action as a treatment for sepsis remains unclear. In this study, we developed a rat model of sepsis using cecal ligation and punc...