Enhancing Paclitaxel Efficacy with Piperine-Paclitaxel Albumin Nanoparticles in Multidrug-Resistant Triple-Negative Breast Cancer by Inhibiting P-Glycoprotein

• Главные авторы: Wenwen Xu (Автор), Yumeng Xiao (Автор), Liang Zheng (Автор), Mingyu Xu (Автор), Xuehua Jiang (Автор), Ling Wang (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2023-11-01T00:00:00Z.
• Предметы: article
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Triple-negative breast cancer (TNBC) is a highly aggressive disease with rapid progression and poor prognosis due to multidrug resistance (MDR). Piperine (PIP) shows promise as a P-gp inhibitor, capable of sensitizing chemotherapeutic drugs and exhibiting antitumor properties. This study explores th...