Polygenic risk for triglyceride levels in the presence of a high impact rare variant

Polygenic risk for triglyceride levels in the presence of a high impact rare variant

Abstract Background Elevated triglyceride (TG) levels are a heritable and modifiable risk factor for cardiovascular disease and have well-established associations with common genetic variation captured in a polygenic risk score (PRS). In young adulthood, the 22q11.2 microdeletion conveys a 2-fold in...

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Main Authors: Shengjie Ying (Author), Tracy Heung (Author), Bhooma Thiruvahindrapuram (Author), Worrawat Engchuan (Author), Yue Yin (Author), Christina Blagojevic (Author), Zhaolei Zhang (Author), Robert A. Hegele (Author), Ryan K. C. Yuen (Author), Anne S. Bassett (Author)
Format: Book
Published: BMC, 2023-11-01T00:00:00Z.
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3rd Floor Main Library

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