Complement activation by in vivo neonatal and in vitro extracorporeal membrane oxygenation

• Main Authors: Johannes Graulich (Author), Joseph Sonntag (Author), Monika Marcinkowski (Author), Karl Bauer (Author), Hans Kössel (Author), Christoph Bührer (Author), Michael Obladen (Author), Hans T. Versmold (Author)
• Format: Book
• Published: Hindawi Limited, 2002-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Complement activation during extracorporeal membrane oxygenation (ECMO) in newborns can be caused by both the underlying disease processes and by blood contact with the ECMO circuit. We investigated the relative importance of these mechanisms by measuring C3a, C5a and sC5b-9 before, during and after...