Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer's disease therapy

• Main Authors: Youssef Dgachi (Author), Hélène Martin (Author), Rim Malek (Author), Daniel Jun (Author), Jana Janockova (Author), Vendula Sepsova (Author), Ondrej Soukup (Author), Isabel Iriepa (Author), Ignacio Moraleda (Author), Emna Maalej (Author), M. Carmo Carreiras (Author), Bernard Refouvelet (Author), Fakher Chabchoub (Author), José Marco-Contelles (Author), Lhassane Ismaili (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In view of the multifactorial nature of Alzheimer's disease (AD), multitarget small molecules (MTSM) represent the most potent and attractive therapeutic strategy to design new drugs for Alzheimer's disease therapy. The new MTSM KojoTacrines (KTs) were designed and synthesized by juxtaposi...