Sulfonylureas exert antidiabetic action on adipocytes by inhibition of PPARγ serine 273 phosphorylation

• Main Authors: Bodo Haas (Author), Moritz David Sebastian Hass (Author), Alexander Voltz (Author), Matthias Vogel (Author), Julia Walther (Author), Arijit Biswas (Author), Daniela Hass (Author), Alexander Pfeifer (Author)
• Format: Book
• Published: Elsevier, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Sulfonylureas (SUs) are still among the mostly prescribed antidiabetic drugs with an established mode of action: release of insulin from pancreatic β-cells. In addition, effects of SUs on adipocytes by activation of the nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ)...