Bicarbonate supplementation as a preventive way in statins-induced muscle damage

• Main Authors: Masaki Kobayashi (Author), Toshiki Kagawa (Author), Katsuya Narumi (Author), Shirou Itagaki (Author), Takeshi Hirano (Author), Ken Iseki (Author)
• Format: Book
• Published: Frontiers Media S.A., 2008-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT - Purpose. The aim of this study was to evaluate the bicarbonate-induced improvement of statins, cerivastatin, simvastatin acid and lovastatin acid -induced apoptosis using rat myoblast cell line (L6) as a model of in vitro skeletal muscle and of cerivastatin-induced muscle damage in vivo s...