Ganoderma spore lipid ameliorates docetaxel, cisplatin, and 5-fluorouracil chemotherapy-induced damage to bone marrow mesenchymal stem cells and hematopoiesis

• Autors principals: Haohui Lin (Autor), Manhon Chung (Autor), Jingchun Sun (Autor), Yi Yang (Autor), Li Zhang (Autor), Xiaohua Pan (Autor), Minghui Wei (Autor), Sa Cai (Autor), Yu Pan (Autor)
• Format: Llibre
• Publicat: BMC, 2024-04-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Abstract Background A triplet chemotherapy regimen of docetaxel, cisplatin, and 5-fluorouracil (TPF) is used to treat head and neck squamous cell carcinoma; however, it is toxic to bone marrow mesenchymal stem cells (BMSCs). We previously demonstrated that Ganoderma spore lipid (GSL) protect BMSCs a...