Changes in liver metabolic pathways demonstrate efficacy of the combined dietary and microbial therapeutic intervention in MASLD mouse model

• Main Authors: Valeria Iannone (Author), Ambrin Farizah Babu (Author), Johnson Lok (Author), Carlos Gómez-Gallego (Author), Giuseppe D'Auria (Author), Ruben Vazquez-Uribe (Author), Troels Holger Vaaben (Author), Mareike Bongers (Author), Santtu Mikkonen (Author), Maija Vaittinen (Author), Ida Tikkanen (Author), Mikko Kettunen (Author), Anton Klåvus (Author), Ratika Sehgal (Author), Dorota Kaminska (Author), Jussi Pihlajamaki (Author), Kati Hanhineva (Author), Hani El-Nezami (Author), Morten Otto Alexander Sommer (Author), Marjukka Kolehmainen (Author)
• Format: Book
• Published: Elsevier, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), is the most prevalent liver disease globally, yet no therapies are approved. The effects of Escherichia coli Nissle 1917 expressing aldafermin, an engineered anal...